Saturday, April 23, 2011

CHEMICAL PROFILE OF ENDOSULFAN






CHEMISTRY OF ENDOSULFAN 


What is endosulfan ? Endosulfan is an off-patent organochlorine insecticide and acaricide This colourless solid has emerged as a highly controversial agrichemical.The IUPAC name for endosulfan is 6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin-3-oxide
Chemical structure of Endosulfan

Endosulfan is a 7:3 mixture of stereoisomers designated α and β. α- and β-endosulfan are conformational isomers arising from the pyramidal stereochemistry of sulfur. α-Endosulfan is the more thermodynamically stable of the two, thus β-endosulfan irreversibly converts to the α form, although the conversion is slow.

 
CHEMICAL SYNTHESIS OF ENDOSULFAN
How endosulfan is synthesized ? Endosulfan  synthesis involves  following steps: It is produced by the Diels-alder reaction Diels-Alder addition of hexachloro-cyclo-pentadiene and cis-butene-1,4-diol in xylene. Subsequently the adduct is hydrolysed to form the cis-diol or di-alcohol. Reaction of this cis-dol with thionyl chloride forms the final product.


DEGRADATION PATHWAY OF ENDOSULFAN



HAZARDS OF ENDOSULFAN













Friday, April 22, 2011

EASY WAY TO PUBLISH YOUR RESEARCH ARTICLES



 THE EFFICIENT AND FAST WAY TO PUBLISH YOUR RESEARCH ARTICLES

Asian Journal of Pharmaceutical and Health Sciences (AJPHS), a peer-reviewed, quarterly published, international print journal / access on web, to encourage young researchers to make fruitful contributions in the fields of pharmaceutical, biological and chemical sciences. The Journal publishes original research work either as a Full Research Paper, or Short Communication and Review Articles.

FOR FURTHER INFORMATION
Editorial office
No 47. Ayodhya Nagar, pallippuram p.o palakkad, Kerala,INDIA
PIN-678006
Email :editorajphs@gmail.com
www.ajphs.com
Tel :+91-9995874675

Thursday, April 21, 2011

List Of Pharmacy Colleges in Kerala 2011

PHARMACY COLLEGES IN KERALA -2011 (Latest)
B.PHARM ADMISSION 2011 KERALA
   
  • Academy Of Pharmaceutical Sciences
(AICTE Approved)
Periyaram, Medical College P.O., Kannur – 670503
Course: B-Pharmacy (Seats: 40)Wesite address: Academy Of Pharmaceutical Sciences : 
click to see the college web site 
  • Al Shifa College Of Pharmacy
(AICTE Approved) (PCI Approved)
Kizhattur Village, Kizhattur Post, Perintalmanna - 679325, Malappuram Dist
Course: B-Pharmacy (Seats: 60) Pharm D (Seats-15) M.Pharm (Pharmaceutics,Pharmaceutical Chemistry,Pharmacy Practice) 
click to see the college web site
  • Amrita College of Pharm. Sciences
(PCI Approved)
(Formerly know as Amrita Instute of Pharmaceutical Sciences)
Amrita Vishwa Vidyapeetham (Deemed University) Amrita Lane, Elamakkara P.O.
Kochi - 682 026
Course: B-Pharmacy (Seats: 60) Pharm D (Seats-15) M.Pharm (Pharmaceutics,Pharmaceutical Chemistry,Pharmacy Practice) 
click to see college web site
  • Cresent College of Pharmacy (AICTE Approved) (PCI Approved)
Mottambram, Puthiyangadi,
P.O. Madayi-Kannur-670 304
Course: Diploma in Pharmacy; (Seats: 60)
B-Pharmacy (Seats: 60)
click to see college web site 

  • College of Pharm. Sciences (AICTE Approved) (PCI Approved)
Medical College Campus, Thiruvananthapuram-695 011
Course: Diploma in Pharmacy; (Seats: 60)
Bachelor in Pharmacy; (Seats: 60)
M.Pharm: Pharmacy Practice (Seats: 8), Pharmaceutical Chemistry (Seats: 10)

click to see college web site 

  • Devaki Amma Memorial College Of Pharmacy (AICTE Approved)
"Malayamkunnath" P.O., Pulliparamba, Chelembra – 673634
Course: Bachelor in Pharmacy; (Seats: 60)

click to see college web site 
  • Deptt. of Pharmaceutical Sciences, Mahatma Gandhi University (PCI Approved)
Cheruvandoor Campus, Ettumanoor - 686 631
Course: Bachelor in Pharmacy; (Seats: 60)

click to see college web site 
  • Ezhuthachan National Academy Pharmacy College (AICTE Approved) (PCI Approved)
Maramamuttom P.O., Neyyattinkara, Thiruvananthapuram Dist – 695131
Course: Bachelor in Pharmacy; (Seats: 60)
click to see college web site
  • Grace College Of Pharmacy (AICTE Approved) (PCI Approved)
Athalur, Kodunthirappuly, Palakkad - 678 004
Course: Bachelor in Pharmacy; (Seats: 40)
click to see college web site
  • JDT Islam College of Pharmacy (AICTE Approved) (PCI Approved)
P.B. No. 1702, Jamiath Hill, Malabar
Calicut - 673 012
Course: Diploma in Pharmacy; (Seats: 60), Bachelor in Pharmacy; (Seats: 60)
click to see college web site 
  • Jamia Salafiya Pharmacy College (AICTE Approved) (PCI Approved)
Salafi Gramam, Pulikkal - 673 637
Course: Diploma in Pharmacy; (Seats: 60), Bachelor in Pharmacy; (Seats: 60)

click to see college web site 
  • Malik Deenar College Of Pharmacy (AICTE Approved)
Seethangoli, Bela Village, Kasargode - 671 321
Course:Bachelor in Pharmacy; (Seats: 60)
Telephone Number : 04994-309440, 221641, 230112, 230306
Fax: 04994-230935
click to see college web site
  • Mar Dioscorus College Of Pharmacy (AICTE Approved)
Alathapa, Sreekariyam, Thiruvananthapuram – 695 017
Course:Bachelor in Pharmacy; (Seats: 60)
click to see college web site
  • Medical College Calicut Dept;of Pharmacy (PCI Approved)
Kozhikode-673 008 
click to see college web site 
  •    National College of Pharmacy (AICTE Approved) (PCI Approved)
    P.O. Manassery, Mukkam
    Kozhikode - 673 602
   Course: Diploma in Pharmacy; (Seats: 60), Bachelor in Pharmacy; (Seats: 60)
 click to see college web site
  • Nehru College Of Pharmacy (AICTE Approved)
Pampadi, Thiruvillwamala, Thrissur – 680597
Course:Bachelor in Pharmacy; (Seats: 60)
click to see college web site
  • Nazareth College Of Pharmacy (AICTE Approved)
Othera P.O., Thiruvalla - 689 546
Course:Bachelor in Pharmacy; (Seats: 60)

click to see college web site 
  • Nirmala Collegeof Pharmacy (AICTE Approved)
Muvattupuzha, Kerala – 686661
Course:Bachelor in Pharmacy; (Seats: 60)
click to see college web site

  • St. James college of Pharmacy  (AICTE Approved)
St. James Medical Academy, River Bank, Chalakudy, Thrissur District, Kerala -680 307
Course:Bachelor in Pharmacy; (Seats: 60)
click to see college web site
  • Pushpagiri College Of Pharmacy (AICTE Approved)
Perumthuzuthy, Tiruvalla – 689107
Course:Bachelor in Pharmacy; (Seats: 60)
click to see college web site
  • R.M. Pharmacy College(AICTE Approved)
Ponnambi, Vellarada, Thiruvananthapuram – 695505
Course:Bachelor in Pharmacy; (Seats: 60)
click to see college web site
  • School Of Medical Education (AICTE Approved)
M.G.University, Cheruvandoor Campus, Ettumanoor, Kottayam - 686560.
Course:Bachelor in Pharmacy;
MPharm Pharmaceutics,pharmacognosy
click to see college web site 
  • St. Joseph College of Pharmacy (AICTE Approved) (PCI Approved)
St. Joseph's Hospital, Muttom
Cherthala - 688 524 Distt. Alapuzha
Course: Diploma in Pharmacy; (Seats: 60), Bachelor in Pharmacy; (Seats: 60)

click to see college web site 
  • The Dale View College Of Pharmacy & Research Centre (AICTE Approved)
Thriuvananthapuram – 695575
Course:Bachelor in Pharmacy; (Seats: 60)
click to see college web site



Friday, April 8, 2011

LABOROTORY SYNTHESIS OF SULFANILAMIDE







PREPARATION OF SULFANILAMIDE
REQUIREMENTS
ü Acetanilide
ü Chlorosulphonic acid
ü Concentrated ammonia solution
ü Dilute sulfuric acid
ü Decolourising carbon
ü Solid sodium bi carbonate
ü alcohol
PRINCIPLE
p-acetamido benzene sulfonyl chloride is an essential intermediate for the synthesis of sulfanilamide drugs. Chlorosulfonation of acetanilide with excess of chlorosulfonic acid affords p-acetamido benzene sulfonyl chloride. Aryl sulfonyl chlorides are converted into corresponding aryl sulfonamides by treatment with conc. ammonia solution or solid ammonium carbonate or by reaction with appropriate amino compounds .p- amino benzene sulfonamide is obtained by converting p-acetamido benzene sulfonyl chloride into the amide with aqueous ammonia and then selectively removing the protecting acetyl group by boiling with aqueous hydrochloric acid.
PROCEDURE (All apparatus must be perfectly dry,chlorosulfonic acid reacts violently with water)
ü Preparation of p-acetamido benzene sulfonyl chloride
Place 5 gm of dry acetanilide into a three necked flask equipped with a condenser, add 16 ml of chlorosulfonic acid slowly in small portions. Shake the flask well and heat the flask on a water bath for 1 hr .Cool and pour this oily mixture as a thin stream with stirring into 100 gm of crushed ice. Rinse with water and broke the ice lumps and stir the mixture for several minutes. Filter it at the pump, wash it with cold water and drain well.
ü Preparation of p-acetamido benzene sulphonamide
Transfer the crude product obtained above into a round bottom flask. Add a mixture of 15ml of ammonia and 15ml of water. Mix the contents of the flask thoroughly with swirling. Heat the mixture for 15 mins (below boiling point.). The sulphonyl chloride is converted into corresponding sulfonamide. Cool on ice, add dil. sulphuric acid until the mixture was just acidic to congo red paper. Collected the product in a buchner funnel.
ü Preparation of p-amino benzene sulphonamide.
Transfer the crude product into 500ml flask and add 5ml of conc. HCl, 10ml of water. Boil the mixture gently under reflux for 10-30 minutes. Cool the mixture to room temperature (should not show any solid) to this add 3gm of charcoal, heat the mixture to boil. Place the filtrate in beaker and continuously add 4gm of solid sodium bicarbonate. Test the filtrate with litmus paper until neutral. Cool it in ice bath and filter the precipitate. Recrystallize from water or alcohol.
Disclaimer: This document is provided to the general public as a courtesy; any individual, institution, or organization who choose to use this document, either in its original or in a modified form, do so at their own risk, author is not liable for injuries or accidents that occur in any lab.









Friday, April 1, 2011

M.Pharm Admission 2011


 M.Pharm admission through GPAT 2011-SCORE  CLICK HERE
Applications are invited for admission to M.Pharm. programme offered by various colleges in INDIA
new NIPER ADMISSION 2011

A. NATIONAL INSTITUTE OF PHARMACEUTICAL
EDUCATION AND RESEARCH (NIPER) M.Pharm admission 2011





Applications are invited for M.Pharm course in Ahmedabad; Guwahati; Hajipur; Hyderabad,Kolkata; Rae Barelli; S.A.S. Nagar

 For prospectus and application form CLICK HERE

1.Manipal college of Pharmaceutical Sciences
MPharm Pharmaceutical Biotechnology
  • MPharm Pharmaceutical Chemistry
  • MPharm Pharmaceutical Marketing
  • MPharm Pharmaceutical Quality Assurance
  • MPharm Pharmaceutics
  • MPharm Pharmacognosy
  • MPharm Pharmacology
  • MPharm Pharmaceutical Administration
  • MPharm Pharmacy Practice

Last Date- 10.05.2011
Application form and information CLICK HERE
2. Amrita Vishwa Vidyapeetham 2011 MPharma Notification
M.Pharm (2 years) (10 seats each):
1. Pharmacy Practise (Hospital and Clinical Pharmacy),
2. Pharmaceutics,
3. Pharmaceutical Chemistry

Eligibility: B.Pharm degree from an Institution approved by the pharmacy council of India (PCI); not less than 50% of the maximum marks for all the subjects of the B.Pharm course from second year to fourth year examinations; candidates with GATE/GPAT score preferred

Admission procedure: Selection is based on the rank obtained in the All India entrance test conducted by Amrita Vishwa Vidyapeetham
Common entrance test: 05th June, 2011, 9.30 a.m. to 12.30 p.m.
Centre for examination: Amrita School of Medicine, Kochi
Admission procedure: Prospectus and application forms will be available from the branches of Dhanalakshmi Bank and Federal Bank from 25th April, 2011 onwards
Cost of application form Rs 1500/-; from the office by speed post/courier Rs 1570/-; download from the website and submit along with a demand draft for Rs 1500/-; demand draft to be drawn in the name of Amrita Vishwa Vidyapeetham, payable at Kochi

Application can be submitted on-line after 25th April, 2011

Requests for applications may be sent to
the admission co-ordinator, office of admissions,
Amrita Health Sciences campus,
Amrita Institute of Medical Sciences and Research centre,
AIMS Ponekkara Post, Kochi, Kerala-682041,
Tel 0484-2858036/8037/5651,
Fax 0484-2802020/2051
Application form and information CLICK HERE




Important dates
Date of commencement of sale of application forms: 25th April, 2011

Last date of sale of application forms: 24th May, 2011

Last date of receipt of duly completed application forms: 28th May, 2011
Date of examination: 05th June, 2011, Sunday
3.K L E University's College of Pharmacy M.Pharm Admission 2011
Admission procedure for B.Pharm and M.Pharm Courses for the year 2011-12 will be through all India entrance test (KLEU-AIET-2011) Scheduled on 7th of may 2011 at various centers across the country
Details CLICK HERE
For online Application CLICK HERE
JSS College of Pharmacy m.Pharm admissionn 2011
Applications are invited from eligible candidates for admission into Master of Pharmacy Program offered at Babasaheb Bhimrao Ambedkar University, Lucknow through Entrance test. M.Pharm : Specialization in Pharmaceutical Sciences. APPLICATION FORM: Download at website www.bbauindia.org, filled-in application form along with Demand Draft of Rs.300/- (Rs. 75/- for SC/ST/PH) drawn in favor of “Finance Officer, Babasaheb Bhimrao Ambedkar University” payable at Lucknow send to: Admission Cell, BBAU, Vidya Vihar Campus, Raebareli Road, Lucknow. LAST DATE FOR SUBMISSION: 30th April, 2011 EXAM CENTRES: Ahmedabad, Bangalore, Bhubaneswar, Bhopal, Chandigarh, Delhi, Guwahati, Hyderabad, Jaipur, Visakhapatnam, Thiruvanantapuram, Kolkata, Nagpur, Patna, Ranchi.  

 

BHU M Tech/ M Pharm admissions 2011

How to Apply
Interested candidates may download the application and the information brochure from the institute’s official websites: www.itbhu.ac.in or www.bhu.ac.in. The application fee for the exam is Rs 500 (non refundable) for General and OBC categories, whereas for SC/ST category the fee is Rs 250 (non-refundable). This fee has to be paid by DD which should be drawn in the favor of “Institute of Technology, BHU” payable at the State Bank of India, BHU, Varanasi (Code-0211). Duly filled application form along with requisite documents and DD should be sent to the respective Head of the Department/ Coordinator of School, Institute of Technology, Banaras Hindu University, Varanasi–221005 (INDIA),
latest by May 9, 2011 for M Tech Programmes and June 13, 2011 for M Pharm Programme.
M.Pharma
M.Pharma (Pharmacognosy)


2)Pharmagnosy - 07 
3)Pharmacology - 07
4)Pharmaceutical Marketing and Management - 10 
5)Quality Assurance - 05
6)Pharmaceutical chemistry - 10 
7)Pharmacy Practice -06
8.SASTRA UNIVERSITY THANJAVUR M.Pharm admission 2011
M.Pharm Pharmacology,
M.Pharm Pharmaceutics,
M.Pharm Pharma analysis
,M.Pharm PHARMA CHEMISTRY
last date of application: June 4 2011
FOR DETAILS CLICK HERE
 
9.Mother Theresa Institute of Health Sciences, Pondicherry.
M.Pharm Pharmaceutics
M.Pharm Pharmaceutical Chemistry
M.Pharm Pharmacology
M.Pharm Pharmacognosy
Contact Mother Theresa Institute of Health SciencesIndira NagarGorimeduPuducherry - 605006Phone:2271200E-Mail: deanmtihs@dataone.in
For detail Click Here


applications are invited for M.Pharm course for the year 2011

For detail Click Here


11.ANNAMALAI UNIVERSITY 2011 M.Pharm Admission

Applications are invited for admission to M.Pharm. programme offered by various Departments in
  • MPharm Pharmaceutical Chemistry
  • MPharm Industrial pharmacy
  • MPharm Quality Assurance
  • MPharm Pharmaceutics
  • MPharm Industrial Pharmacognosy
  • MPharm Pharmacology
  • MPharm Pharmacy Practice

For detail Click Here
M.Pharm admission through GPAT SCORE COLLEGE LIST CLICK HERE
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