Saturday, April 23, 2011

CHEMICAL PROFILE OF ENDOSULFAN






CHEMISTRY OF ENDOSULFAN 


What is endosulfan ? Endosulfan is an off-patent organochlorine insecticide and acaricide This colourless solid has emerged as a highly controversial agrichemical.The IUPAC name for endosulfan is 6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin-3-oxide
Chemical structure of Endosulfan

Endosulfan is a 7:3 mixture of stereoisomers designated α and β. α- and β-endosulfan are conformational isomers arising from the pyramidal stereochemistry of sulfur. α-Endosulfan is the more thermodynamically stable of the two, thus β-endosulfan irreversibly converts to the α form, although the conversion is slow.

 
CHEMICAL SYNTHESIS OF ENDOSULFAN
How endosulfan is synthesized ? Endosulfan  synthesis involves  following steps: It is produced by the Diels-alder reaction Diels-Alder addition of hexachloro-cyclo-pentadiene and cis-butene-1,4-diol in xylene. Subsequently the adduct is hydrolysed to form the cis-diol or di-alcohol. Reaction of this cis-dol with thionyl chloride forms the final product.


DEGRADATION PATHWAY OF ENDOSULFAN



HAZARDS OF ENDOSULFAN













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