Tinospora cordifoliaTinospora cordifolia commonly known as Guduchi is one of the most valuable medicinal herbs of ayurveda. According to the Ayurvedic lexicons Tinospora cordifolia is referred to as 'Amrita'. The term 'Amrita' is attributed to this drug in recognition of its ability to impart youthfulness, vitality and longevity to its patron. In modern medicine it is well known for its hepatoprotective, adaptogenic and immunomodulatory activities.
Kupffer cells are major determinants of outcome of liver injury. Their activity was therefore studied in a model of chronic liver disease. The effect of Tinospora cordifolia, with proven hepatoprotective activity, was evaluated on Kupffer cell function, using carbon clearance test as a parameter. Antihepatotoxic activity of Tinospora cordifolia was studied in albino rats intoxicated with CCl4.
Liver function was assessed based on morphological, biochemical (SGPT, SGOT, Serum alkaline phosphatase, Serum bilirubin) and functional (Pentobarbitone sleep time) tests. Efficacy of Tinospora cordifolia as a sole constituent in goats liver were studied. Results revealed clinical and hematobiochemical improvement at the later stages in Tinospora cordifolia treated goats, indicating that it has got hepatoprotective action
Kupffer cells are major determinants of outcome of liver injury. Their activity was therefore studied in a model of chronic liver disease. The effect of Tinospora cordifolia, with proven hepatoprotective activity, was evaluated on Kupffer cell function, using carbon clearance test as a parameter. Antihepatotoxic activity of Tinospora cordifolia was studied in albino rats intoxicated with CCl4.
Liver function was assessed based on morphological, biochemical (SGPT, SGOT, Serum alkaline phosphatase, Serum bilirubin) and functional (Pentobarbitone sleep time) tests. Efficacy of Tinospora cordifolia as a sole constituent in goats liver were studied. Results revealed clinical and hematobiochemical improvement at the later stages in Tinospora cordifolia treated goats, indicating that it has got hepatoprotective action
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