Friday, December 19, 2008

Phyllanthus niruri

HEPATOPROTECTIVES, LIVER TONIC, ANTI HEPATOTOXIC

Phyllanthus niruri
Bhuiamalaki, botanically known has Phyllanthus niruri is a member of Euphorbiaceae family. The decoction of the plant has historically being used in jaundice. In a preliminary study, carriers of hepatitis B virus were treated with a preparation of the plant Phyllanthus niruri for 30 days. 22 of 37 (59%) treated patients had lost hepatitis B surface antigen when tested 15-20 days after the end of the treatment compared with only 1 of 23 (4%) placebo-treated controls. Some subjects have been followed for up to 9 months. In no case has the surface antigen returned. Studies also revealed that Phyllanthus niruri exhibits antiviral actions on Hepatitis B in human subjects and in vitro.
Preclinical studies demonstrates that an extract of the Phyllanthus niruri plant inhibits endogenous DNA polymerase of hepatitis B virus and binds to the surface antigen of hepatitis B virus. Extracts of Phyllanthus niruri have been shown to exert hepatoprotective effect against carbon tetrachloride induced liver cell damage in rabbits. Pre-treatment with extract of Phyllanthus niruri, reduced paracetamol-induced acute liver damage in rats as monitored by estimating the serum transaminases (SGOT and SGPT), bilirubin and histopathological changes in the livers.


Withania somnifera

HEPATOPROTECTIVE AGENTS, LIVER TONIC, ANTI HEPATOTOXICWithania somnifera

Withania somnifera (L) Dunal (Solanaceae), commonly called Ashwagandha (Sanskrit) is an Ayurvedic Indian medicinal plant, which has been widely used as a home remedy for several ailments.
Mechanism by which the W. somnifera exerts a hepatoprotective effect in a hyperammonemic condition could be attributed to (i) presence of natural antioxidants, (ii) its free radical scavenging and antioxidant properties and (iii) excess removal of urea related compounds. The exact underlying mechanism is still unclear and further research is needed.

Boerhavia diffusa

HEPATOPROTECTIVE AGENTS, LIVER TONIC, ANTI HEPATOTOXICBoerhavia diffusa

The roots of Boerhavia diffusa, commonly known as 'Punarnava', are used by a large number of tribes in India for the treatment of various hepatic disorders and for interna inflammation. Anodectal data has lso reported effectiveness of Boerhavia diffusa incases of oedema and ascites resulting from early cirrhosis of the liver and chronic peritonitis. . A proprietory hepatotonic herbal formulation containing Boerhavia diffusa as one of the major ingredient offered significant protection against decrease in haemoglobin percentage R.B.C. and W.B.C counts and the various liver microsomal enzymes.

Tinospora cordifolia

HEPATOPROTECTIVE AGENTS, LIVER TONIC, ANTI HEPATOTOXIC Tinospora cordifolia

Tinospora cordifolia commonly known as Guduchi is one of the most valuable medicinal herbs of ayurveda. According to the Ayurvedic lexicons Tinospora cordifolia is referred to as 'Amrita'. The term 'Amrita' is attributed to this drug in recognition of its ability to impart youthfulness, vitality and longevity to its patron. In modern medicine it is well known for its hepatoprotective, adaptogenic and immunomodulatory activities.
Kupffer cells are major determinants of outcome of liver injury. Their activity was therefore studied in a model of chronic liver disease. The effect of Tinospora cordifolia, with proven hepatoprotective activity, was evaluated on Kupffer cell function, using carbon clearance test as a parameter. Antihepatotoxic activity of Tinospora cordifolia was studied in albino rats intoxicated with CCl4.
Liver function was assessed based on morphological, biochemical (SGPT, SGOT, Serum alkaline phosphatase, Serum bilirubin) and functional (Pentobarbitone sleep time) tests. Efficacy of Tinospora cordifolia as a sole constituent in goats liver were studied. Results revealed clinical and hematobiochemical improvement at the later stages in Tinospora cordifolia treated goats, indicating that it has got hepatoprotective action

Silybum marianum

HEPATOPROTECTIVE AGENTS, LIVER TONIC, ANTI HEPATOTOXIC


Silybum marianum



Blessed Milk Thistle (Silybum marianum) is a milk thistle, a plant of the Asteraceae family. This fairly typical thistle has red to purple flowers and shiny pale green leaves with white veins. Originally a native of Southern Europe through to Asia, it is now found throughout the world. The medicinal parts of the plant are the ripe seeds.


Its traditional use as a liver tonic has been supported by research showing that it contains constituents that protect liver cells from chemical damage. Historically, this herb has been used in Europe as a liver tonic, and current phytotherapy indicates its use in a whole range of liver and gallbladder conditions, including hepatitis and cirrhosis. It may also have value in the treatment of chronic uterine problems. A wealth of research done in Germany is revealing exciting data about reversal of toxic liver damage, as well as protection from potential hepato-toxic agents.


A study conducted in 85 patients revealed that silybin conjugated with vitamin E and phospholipids could be used as a complementary approach to the treatment of patients with chronic liver damage.

Tuesday, December 16, 2008

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Wednesday, December 10, 2008

UPCOMING SEMINARS,CONFERENCES AND EVENTS


FORTHCOMING SEMINARS,CONFERENCES AND EVENTS
IN PHARMACY June 2009 (INDIA) UPDATED

 FOR 2011 UPDATES CLICK HERE





 


SEMINARS IN NOVEMBER 2008
1.First International Conference On Pharmacovigilance And Clinical Data Management
Date: 2-5 November 2008
Venue: Full day workshop on 2 November at Cognizant Hiranandani Business Park, Powai, Mumbai followed by a three day conference from 3 -5 November, at The Residence Hotel, Powai Mumbai.

2.Theoretical and Practical Course "Transgene Expression in Plants"
Organiser: International Centre for Genetic Engineering and Biotechnology (ICGEB, New Delhi, India)
Date:10 - 13 November 2008
3.2nd Indo - US meeting on Mitochondrial Research & Medicine
Date:12-14 November 2008
Venue-ManipalUniversity,Manglore
http://www.manipal.edu/manipalsite/Users/globalpage.aspx?pgid=52
4.National Seminar on Recent Advances in Pharmaceutical Analysis
Date: 13-15 November 2008.
Venue: PES College of Pharmacy,Hanumanth Nagar,Banglore.
5. AICTE Sponsored one day seminar on "Recent Advances in Pharmaceutical Sciences."
Date:November 14 -2008
venue:Erode College Of Pharmacy,Erode.
http://ecperode.in/seminar/
6.International Conference On New Developments In Drug Discovery From Natural Products And Traditional Medicines.
Venue:- NIPER ,S.A.S.Nagar,Punjab,India
Date:16 th November -20 th November 2008
7.Biology in the new millennium “Indo-US conference on translational medicine and infectious diseases”
Date-17-20 November, 2008
Venue - National Institute of Immunology, New Delhi, India .
http://www.nii.res.in/
8.bioLOGIC India 2008: India’s most influential biopharmaceutical meeting
venue:Marriott hotel, Hyderabad.
Date:17-20 november 2008
http://www.terrapinn.com/2008/bioindia/
8.INDO-RUSSIAN WORKSHOPon Self - propagating High Temperature Synthesis
Date:Nov 27 - 29, 2008
venue:The Materials Research Centre (MRC),Banglore.
http://mrc.iisc.ernet.in/
9.National Seminar on Cancer - Biology and Development of New Chemical Entities
Date:20-22 november 2008
Venue:PSG College of Pharmacy,Coimbatore,Tamil Nadu
http://www.psgpharma.com/natsemi_cancer.html
10.National Seminar and Workshop on "Metabolic Networks and Drug Discovery"
Date:28-11-2008 to 30-11-2008
Venue:Banarus Hindhu University
11.P-Mec India
Date: 27-30 November 2008
Venue: Bombay Exhibition Centre-NSE Exhibition Complex, Mumbai.
http://www.cphi-india.com/content/P-MECIndia.aspx
12.Seventh National Workshop on “Simple Diagnostic Methods in Clinical Microbiology” Date:25th to 29th November 2008
Venue: Department of Microbiology Jawaharlal Institute of Postgraduate Medical Education & Research, Pondicherry.
http://www.jipmer.edu/
SEMINARS IN DECEMBER 2008
13.Recent Techniques in Structural and Functional Genomics
Date:December 1 -10, 2008
Venue:Central Institute of Medicinal and Aromatic Plants Lucknow – 226 015
http://www.cimap.res.in/WinterSchool_2008.html
14.DIA's 3rd Annual Conference on Drug Discovery and Clinical Development in India: Scientific, Regulatory, and Social Frontiers
Date:07 Dec 2008 - 10 Dec 2008
Venue:Renaissance Mumbai Hotel & Convention Centre,
2 & 3B, Near Chinmayanand, Ashram, Powai400087 MumbaiIndia
http://www.diahome.org/DIAHome/
15.R & D Conference 2008
Venue:India habitat centre N.Delhi
Date: december 6 -10 2008
http://www.cdriindia.org/endoconf2008/csirconfdec08.pdf
15.International Conference on Natural Products in Health & 21st Annual Conference of The Indian Society for Atherosclerosis Research.
Date: 8th - 10th December , 2008
Venue:Annamali university,Chidambaram.
http://annamalaiuniversity.ac.in/conference_bio_chem.htm
16.National Symposium On“Recent Advances inFemale Reproductive Health Research” Date:December 11-12, 2008
Venue:Central drug research institute,lucknow
http://www.cdriindia.org/endoconf2008/endosymp2008-1.pdf
17.60th Indian Pharmaceutical Congress (IPC) 2008
Date: 12-14 December, 2008
Venue: Netaji Subash Institute of Technology, New Delhi
18.Science Conclave With Nobel Prize Winners (Interaction Meet of Young Scientists/Students/Teachers with Nobel Laureates/Eminent Scientists)
Date:15-21 December 2008
Venue:Indian institute of information technology,Allahabad.
19.International Conference On Biotechnological Approaches To Neuroimmunomodulation And Infectious Diseases (Icbanid)
Date- December 11-13, 2008.
Venue-National Institute of Pharmaceutical Education and Research Sector-67, Phase-X, S. A. S. Nagar-160 062, Punjab,
http://niper.nic.in/
20.IISc Centenary Conference
Date:13-16
December 2008
Venue: Indian Institute Of Science,Banglore
http://www.iisc.ernet.in/centenary-conf/
21.A Satellite Alexander Hollaender Workshop on "Genetic Toxicology"
Da7te: December 15 - 17, 2008.
Venue:Indian Institute of Toxicology Research (IITR), Lucknow
http://www.iitrindia.org/ForthcomingEvents.html
22.International Conference On Translational Pharmacology and 41 st Annual Conference Of Indian Pharmacological Society
Date:December18-20 2008
Venue:AIIMS ,N.Delhi
23.Meditel 2008 (new)
Organised by Medical Computer Society of India
Date : 19th - 20th DECEMBER, 2008
Venue: Sri Ramchandra Medical College & Research Institute, Porur,Chennai- 600116.
http://www.meditel2008.com/
SEMINARS IN JANUARY 2009
24. 96 th Indian Science Congress
Date: January 3-7 2009
Venue:North-Eastern Hill University (NEHU) ,Shillong-793022
http://www.isc2009nehu.com/
25.INTERNATIONAL CONFERENCE ON MOLECULAR MEDICINE With special reference to therapeutic applications
Organised by:The Laila Pharmaceuticals Pvt Ltd, Chennai In Association With:Indian Institute of Technology Madras,India,Florida International University, Miami, FL, USA and Sri Ramachandra University and Stella Maris College for women.
Date:January 18th - 20th, 2009
Venue: IIT Madras
http://molmed2009.com/
26.ICT Innovations
Date:January 22-23, 2009,
Venue:FICCI, Federation House, New Delhi
http://www.indiarnd.com/
26.21st Kerala Science Congress
Date: 28-31 January 2009
Venue: C. Kesavan Memorial Hall, Kollam,Kerala
http://www.ksc.kerala.gov.in/venueanddate.htm
27.International Conference on Interplay of Chemical and Biological Sciences: Impact on Health and Environment
Date-26th February - 1st March 2009
Venue- Delhi University, Delhi Organized by-Indian Society of Chemists & Biologists, India and Delhi University http://www.iscbindia.org/conference.htm
SEMINARS IN FEBRUARY 2009
28.Drug metabolism and pharmacokinetic (DMPK)symposium
Date:13 and 14 february 2009
venue:NIPER ,S.A.S.Nagar
http://niper.nic.in/index.htm
29., Efficacy and Safety” International conference on Herbal Medicine – “Evaluation of Quality
Date:February 26 , 27 & 28th (Thursday,Friday & Saturday), 2009
Venue:J.N Tata auditorium,National science seminar complex,Indian Institute of Science,Banglore
http://www.herbalconference2009.com/
Date: Feb. 24th-28th, 2009
Venue-niper,Mohali
31.5th Nutraceutical Summit 2009
Date:February 19-21, 2009
Venue:'The Taj President', Mumbai,
32.Conference On transdermal and topical delivery of dermaceuticals and cosmaceutical products.
Date: February 20-21 2009.
Venue: Mumbai ,India.
31.National symposium in animal models in biomedical research-ethical and welfare issues (new)
Date:25 and 26 th february 2009
Venue: CDRI ,Lucknow
SEMINARS IN MARCH 2009
32.IPA Convention 2009
Date:march 14-15 2009
venue: DIPSER .N.Delhi
33.1 st symposium on medicinal Chemistry and Pharmaceutical Sciences(new)
Date :MARCH 24-26, 2009
34.workshop on 'computational chemistry and chemoinformatics approaches in modern drug discovery'(new)
Dates:18 - 21 March, 2009
Venue: IIITM-K, Nila Building, Technopark, Trivandrum
35.International Conference on Open Source for Computer Aided Drug Discovery(new)
Date :22-26 March, 2009
SEMINARS IN APRIL 2009

33.Workshop on "Computer Aided Drug Design and Molecular Modeling"
Date: 01-04-2009 to 03-04-2009
Dr. S.K. Shrivastava, Organising Secretary of the Workshop, Deptt. of Pharmaceutics, I.T., BHU
http://bhu.ac.in/seminar/seminar.htm
34.Banglore Bio 2009
Date:April 15-17 2009
Venue:Banglore International exibition centre,Tumkur road,Banglore
34.2-day seminar on Stem Cell Research and Therapy'(new)
Date:April 13 to 14, 2009
Venue:Assocham House, New Delhi
34.Workshop on METHODS IN EPIDEMIOLOGIC, CLINICAL & OPERATIONS RESEARCH (MECOR) (new)
31 May- 6 June 2009
venue-National Institute of Epidemiology (NIE/ICMR), Chennai
http://www.nie.gov.in/MECOR.pdf

SEMINARS IN August 2009
31. AICTE SPONSORED STAFF DEVELOPMENT PROGRAMME
"PHARMACEUTICAL EDUCATION A GLOBAL PROSPECTIVE
Date: 3 -14 August 2009
Venue: Al Shifa College of Pharmacy, Poonthavanam .P.O
Kizhattur, Perinthalamanna,Kerala.Pin- 67932
For details and application form CLICK HERE
32.DEPARTMENT OF TECHNOLOGY
International Conference on Challenges in Biotechnology and Food Technology

August 26 – 28th , 2009
ORGANISED BY-Department of Technology,Faculty of Engineering and Technology,Annamalai University,Annamalai Nagar – 608 002
http://annamalaiuniversity.ac.in/conference_tech_icbf2009.htm

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Monday, December 1, 2008

MOON,VENUS AND JUPIETR MAKES THE SKY SMILE

SMILEY FACE MOON DECEMBER 1 2008

Venus and Jupiter, will be close together in the evening sky, forming a spectacular double. The two are closest together on Monday December 1st, with Venus lying about 2 degrees to the South (left) of Jupiter. On the same night the Crescent Moon will appear just beneath them, forming a “Smiley Face”.It will be visible for three or four days and it can be seen from all parts of the world ,but will be more clear from Newyork and Hongkong.Don't waste this precious moments because it is rare